Supplements

Informational overview of supplements often discussed alongside repurposed-drug research. Evidence is mostly preclinical — not medical advice, diagnosis, or a treatment protocol. Always consult a qualified healthcare professional.

Entries below cover benefits, typical dosages, and proposed mechanisms (inflammation, oxidative stress, detox support). Rows are grouped by synergistic pairings with pastel color-coding. Human clinical confirmation is limited.

Supplement summary

Jump by category, or click a name for detail.

Category Supplement Potential benefits Typical dosage Notes
Detox Milk Thistle Supports liver detoxification, antioxidant, may aid chemotherapy recovery 150-300 mg/day (silymarin) Active ingredient is silymarin, best taken with food.
Sulforaphane Supports detoxification, antioxidant, may have anti-cancer properties 10-40 mg/day (from supplements) Found in broccoli sprouts and cruciferous vegetables.
Anti-Cancer Black Seed Oil Anti-inflammatory, antioxidant, potential anti-cancer properties 1-3 tsp/day (5-15 mL) Active compound is thymoquinone; best taken with food.
Curcumin Anti-inflammatory, antioxidant, potential cancer-fighting properties 500-2000 mg/day Best absorbed with black pepper extract (piperine).
Inflammation Quercetin Antioxidant, anti-inflammatory, may help suppress tumor growth 500-1000 mg/day Often combined with bromelain for better absorption.
Bromelain Anti-inflammatory, supports digestion, potential anti-cancer properties 500-1000 mg/day Often paired with quercetin; derived from pineapple.
Antioxidant EGCG (Green Tea Extract) Antioxidant, supports immune function, may inhibit cancer cell growth 200-800 mg/day Best taken on an empty stomach for maximum absorption.
Vitamin C Antioxidant, supports immune function, may enhance cancer therapy 1000-2000 mg/day (oral); 10-50 g IV (cancer-related) High doses may require IV for cancer effects.
Cellular Resveratrol Antioxidant, supports cellular health, potential anti-cancer effects 100-500 mg/day Found in red grapes, wine, and Japanese knotweed.
Omega-3 Fatty Acids (EPA/DHA) Anti-inflammatory, supports immune function, may inhibit tumor growth 1000-3000 mg/day (EPA+DHA) Found in fish oil; best with low omega-6 intake.
Immunity Vitamin D3 Supports immune function, may reduce cancer risk 1000-4000 IU/day Best taken with fat for proper absorption.
Astragalus Immune-boosting, anti-inflammatory, potential anti-cancer effects 500-1000 mg/day (extract) Often used in TCM; best as root extract.
Stress Melatonin Regulates sleep, supports immune function, potential anti-cancer effects 3-20 mg/day (cancer-related) Higher doses may be needed for therapeutic effects.
Ashwagandha Adaptogenic, anti-stress, potential anti-cancer properties 300-600 mg/day (extract) Best taken at night; may enhance sleep.
Gut Berberine Supports metabolic health, may have anti-cancer properties 500-1500 mg/day Commonly used for blood sugar regulation and gut health.
Ginger Anti-inflammatory, antioxidant, may reduce nausea and cancer growth 1000-2000 mg/day (extract) Can be taken as tea or capsules.
Anti-Inflamm Nattokinase Supports circulation, anti-inflammatory, potential anti-cancer effects 100-200 mg/day (2000-4000 FU) Derived from fermented soybeans (natto); take on empty stomach.
Turmeric Anti-inflammatory, antioxidant, potential anti-cancer properties 500-2000 mg/day (curcumin extract) Active compound is curcumin; often paired with piperine.
Detox+ Zeolite Supports detoxification, may trap toxins and heavy metals 1-5 g/day Micronized clinoptilolite form; mix with water.
Castor Oil Anti-inflammatory, supports detox via lymphatic drainage Apply pack 1-2 hours/day Used topically in packs; internal use requires caution.
Metabolic MCT Oil Supports ketosis, anti-inflammatory, potential anti-cancer effects 1-3 tbsp/day (15-45 mL) Derived from coconut oil; start low to avoid GI upset.
DMSO Anti-inflammatory, enhances drug delivery, potential anti-cancer effects Varies (e.g., 50-70% solution topically) Dilute for topical use; medical-grade only.
Support Selenium Antioxidant, supports immune function, may reduce cancer risk 100-200 mcg/day Avoid excess (>400 mcg/day) due to toxicity.
Cleanse Gum Spirits of Turpentine Antimicrobial, anti-inflammatory, potential detox support 1-3 drops/day (with carrier like sugar) Pure pine-derived; use with caution, small doses.
Oxidative Chlorine Dioxide Antimicrobial, oxidative agent, controversial anti-cancer claims Varies (e.g., MMS protocols, controversial) Highly debated; use under strict guidance if at all.
Cancer Artemisinin (from Wormwood) Anti-cancer, may induce apoptosis in cancer cells 50-200 mg/day, higher for cancer (consult provider) Derived from Artemisia annua; use under medical supervision due to potential toxicity.
Allium Garlic Anti-cancer, antimicrobial, supports cardiovascular health 1-2 cloves/day or 600-900 mg extract daily Contains allicin; best consumed raw or as extract.

How supplements help and why they may affect cancer

Milk Thistle

How it helps
Supports liver detoxification, antioxidant, may aid chemotherapy recovery
Typical dosage
150-300 mg/day (silymarin) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Protects liver from chemo toxicity, reduces oxidative damage. Active ingredient is silymarin, best taken with food. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Sulforaphane

How it helps
Supports detoxification, antioxidant, may have anti-cancer properties
Typical dosage
10-40 mg/day (from supplements) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Activates Nrf2, enhancing detox and reducing oxidative stress in tumors. Found in broccoli sprouts and cruciferous vegetables. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Black Seed Oil

How it helps
Anti-inflammatory, antioxidant, potential anti-cancer properties
Typical dosage
1-3 tsp/day (5-15 mL) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Induces apoptosis via p53 and caspase activation, inhibits tumor growth. Active compound is thymoquinone; best taken with food. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Curcumin

How it helps
Anti-inflammatory, antioxidant, potential cancer-fighting properties
Typical dosage
500-2000 mg/day (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Inhibits NF-κB and COX-2 pathways, reducing inflammation and tumor growth. Best absorbed with black pepper extract (piperine). Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Quercetin

How it helps
Antioxidant, anti-inflammatory, may help suppress tumor growth
Typical dosage
500-1000 mg/day (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Blocks PI3K/Akt signaling, inducing apoptosis in cancer cells. Often combined with bromelain for better absorption. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Bromelain

How it helps
Anti-inflammatory, supports digestion, potential anti-cancer properties
Typical dosage
500-1000 mg/day (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Inhibits NF-κB and COX-2, reduces metastasis and tumor invasion. Often paired with quercetin; derived from pineapple. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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EGCG (Green Tea Extract)

How it helps
Antioxidant, supports immune function, may inhibit cancer cell growth
Typical dosage
200-800 mg/day (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Downregulates VEGF, inhibiting angiogenesis and tumor spread. Best taken on an empty stomach for maximum absorption. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Vitamin C

How it helps
Antioxidant, supports immune function, may enhance cancer therapy
Typical dosage
1000-2000 mg/day (oral); 10-50 g IV (cancer-related) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Generates hydrogen peroxide in high doses, selectively toxic to cancer cells. High doses may require IV for cancer effects. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Resveratrol

How it helps
Antioxidant, supports cellular health, potential anti-cancer effects
Typical dosage
100-500 mg/day (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Activates SIRT1 and p53, promoting apoptosis and cell cycle arrest. Found in red grapes, wine, and Japanese knotweed. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Omega-3 Fatty Acids (EPA/DHA)

How it helps
Anti-inflammatory, supports immune function, may inhibit tumor growth
Typical dosage
1000-3000 mg/day (EPA+DHA) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Reduces prostaglandin E2 via COX inhibition, induces apoptosis. Found in fish oil; best with low omega-6 intake. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Vitamin D3

How it helps
Supports immune function, may reduce cancer risk
Typical dosage
1000-4000 IU/day (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Regulates cell differentiation and proliferation via VDR signaling. Best taken with fat for proper absorption. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Astragalus

How it helps
Immune-boosting, anti-inflammatory, potential anti-cancer effects
Typical dosage
500-1000 mg/day (extract) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Stimulates NK cells and T-cells, inhibits tumor growth. Often used in TCM; best as root extract. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Melatonin

How it helps
Regulates sleep, supports immune function, potential anti-cancer effects
Typical dosage
3-20 mg/day (cancer-related) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Inhibits tumor metabolism and enhances immune surveillance. Higher doses may be needed for therapeutic effects. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Ashwagandha

How it helps
Adaptogenic, anti-stress, potential anti-cancer properties
Typical dosage
300-600 mg/day (extract) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Inhibits STAT3 and NF-κB, promotes apoptosis. Best taken at night; may enhance sleep. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Berberine

How it helps
Supports metabolic health, may have anti-cancer properties
Typical dosage
500-1500 mg/day (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Targets AMPK, disrupting cancer cell energy production. Commonly used for blood sugar regulation and gut health. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Ginger

How it helps
Anti-inflammatory, antioxidant, may reduce nausea and cancer growth
Typical dosage
1000-2000 mg/day (extract) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Inhibits NF-κB and COX-2, induces apoptosis. Can be taken as tea or capsules. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Nattokinase

How it helps
Supports circulation, anti-inflammatory, potential anti-cancer effects
Typical dosage
100-200 mg/day (2000-4000 FU) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Reduces fibrin, may inhibit metastasis and tumor angiogenesis. Derived from fermented soybeans (natto); take on empty stomach. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Turmeric

How it helps
Anti-inflammatory, antioxidant, potential anti-cancer properties
Typical dosage
500-2000 mg/day (curcumin extract) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Inhibits NF-κB and STAT3, suppresses tumor growth and metastasis. Active compound is curcumin; often paired with piperine. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Zeolite

How it helps
Supports detoxification, may trap toxins and heavy metals
Typical dosage
1-5 g/day (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
May reduce oxidative stress and toxin load in tumor microenvironment. Micronized clinoptilolite form; mix with water. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Castor Oil

How it helps
Anti-inflammatory, supports detox via lymphatic drainage
Typical dosage
Apply pack 1-2 hours/day (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
May enhance immune response and reduce tumor inflammation. Used topically in packs; internal use requires caution. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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MCT Oil

How it helps
Supports ketosis, anti-inflammatory, potential anti-cancer effects
Typical dosage
1-3 tbsp/day (15-45 mL) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Provides ketones, starving glucose-dependent cancer cells. Derived from coconut oil; start low to avoid GI upset. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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DMSO

How it helps
Anti-inflammatory, enhances drug delivery, potential anti-cancer effects
Typical dosage
Varies (e.g., 50-70% solution topically) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
May disrupt cancer cell membranes and enhance chemo penetration. Dilute for topical use; medical-grade only. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Selenium

How it helps
Antioxidant, supports immune function, may reduce cancer risk
Typical dosage
100-200 mcg/day (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Enhances glutathione peroxidase, protects DNA, induces apoptosis. Avoid excess (>400 mcg/day) due to toxicity. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Gum Spirits of Turpentine

How it helps
Antimicrobial, anti-inflammatory, potential detox support
Typical dosage
1-3 drops/day (with carrier like sugar) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
May disrupt cancer cell metabolism via oxidative stress. Pure pine-derived; use with caution, small doses. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Chlorine Dioxide

How it helps
Antimicrobial, oxidative agent, controversial anti-cancer claims
Typical dosage
Varies (e.g., MMS protocols, controversial) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Proposed to oxidize cancer cells, lacks robust evidence. Highly debated; use under strict guidance if at all. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Artemisinin (from Wormwood)

How it helps
Anti-cancer, may induce apoptosis in cancer cells
Typical dosage
50-200 mg/day, higher for cancer (consult provider) (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Targets iron-rich cancer cells, generating free radicals to induce cell death. Derived from Artemisia annua; use under medical supervision due to potential toxicity. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Garlic

How it helps
Anti-cancer, antimicrobial, supports cardiovascular health
Typical dosage
1-2 cloves/day or 600-900 mg extract daily (common supplement ranges / preclinical context — therapeutic cancer doses may differ and need medical oversight)
Why it may help with cancer
Inhibits cancer-causing substances, enhances DNA repair, induces cell death. Contains allicin; best consumed raw or as extract. Effects are mainly from lab or animal models — potential, not proven human efficacy.

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Support against Herxheimer reactions

Herxing can occur when toxins are released faster than the body clears them (fatigue, inflammation, flu-like symptoms). These notes summarize how each entry may help with detox load or inflammation — exploratory only.

Edited Oct 1, 2026